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Andrew Buelt, DO and Joe Weatherly, DO

Among patients at high risk for cardiovascular events but without diabetes, targeting a systolic blood pressure of less than 120 mmHg, as compared with less than 140 mm Hg, resulted in lower rates of fatal and nonfatal major cardiovascular events and death from any cause. The downside, there was a commensurate and sometimes greater risk of adverse events.

Published in the November 9, 2015 NEJM, A Randomized Trial of Intensive versus Standard Blood-Pressure Control.

Reference

SPRINT Research Group. “A Randomized Trial of Intensive versus Standard Blood-Pressure Control.” The New England journal of medicine (2015).